The shootings all took place in south Omaha on Saturday, the same day the city kicked off the College World Series — the NCAA championship for baseball.
Officers responded to the first shooting at 2:03 p.m. That incident left one person in critical condition, Omaha police said.
At 2:23 p.m., police responded to another shooting across town that also left one person in critical condition.
Four minutes later, officers arrived at the scene of a third shooting. One person was hospitalized but later died, police said.
A fourth shooting occurred around 2:30 p.m., leaving one person dead. A neighbor followed the suspect and updated police on his location.
When officers caught up with the suspect, a gunbattle ensued. Police fatally shot the suspect, but no officers were injured.
Omaha police said it was unclear whether all the shootings were related.